Arthritis: The ‘happy hormone’ can help with treatment
rheumatoid arthritis It is the most common rheumatic infection joint disease. The disease leads to the destruction of cartilage and adjacent bones. The role of the Prophet’s material has been searched for years dopamine in disease progression and development. Now it is said that the so-called “happiness hormone” The bone metabolism It can affect arthritis.
The so-called “happiness hormone” dopamine controls many processes in the brain associated with controlling movements, emotions and motivation. In addition, dopamine indirectly affects the human defense system, as the Leibniz Institute for Labor Research at TU Dortmund (IfADo) explains about it. website. And it can affect bone metabolism in osteoarthritis, according to a research paper published in the journal “cellsThe published study appears.
The role of dopamine in bone metabolism
Today there are many treatments that can significantly reduce the effects of rheumatoid arthritis (RA). Bone loss and bone loss (Osteoporosis) is still an issue, according to an existing issue message From IfADo.
the majority Osteoporosis treatments They aim to prevent bone loss, while few treatments are able to promote the formation of new bone tissue to restore already lost bone structure.
Based on previous studies, researchers From IfADo has examined the role of the neurotransmitter dopamine in the bone metabolism of patients with rheumatoid arthritis in more detail.
Scientists have come to the conclusion that dopamine is essential for new therapeutic approaches to control bone loss Can be used in rheumatoid arthritis.
Dopamine receptors are found in bone tissue
The group of Professor Dr. In a current project, Silvia Cappelino investigated the importance of the biochemical dopamine to the bone formation process in rheumatoid arthritis. Dopamine is a neurotransmitters The central nervous system that controls movement, emotions, and cognition.
Dopamine receptors, the signal-receiving unit of the neurotransmitter, were immediate bone tissue have found.
Attend the dopamine receptors In rheumatoid arthritis patients indicates that dopamine also plays a role in the metabolic physiology of human bone.
Therefore, researchers present a file hypothesis showed that the signaling pathway activated by dopamine in inflamed joints also affects bone metabolism in rheumatoid arthritis.
From this, experts concluded that decoding the signaling pathways that dopamine controls bone metabolism paved the way for new pathways. Therapeutic methods To control bone loss. (ad)
Author and source information
This text complies with the requirements of the specialized medical literature, clinical guidelines, and current studies and has been examined by medical professionals.
- Leibniz Institute for Labor Research at the University of Dortmund: Dopamine can affect bone metabolism in osteoarthritis (Accessed: 08.06.2022), Leibniz Institute for Labor Research at TU Dortmund
- Schwinditch, E.; Salinas Tejedor, L.; Schmitz, c. Rickert, M.; Steinmeier, J.; Rehart, S.; Tsiame, S.; Brown, J.; Baraliakos, X.; Reinders, J.; Newman, E.; Muller-Ladner, Yu; Capellino, S: Modulation of dopamine receptors on osteoblasts as a potential therapeutic strategy to induce bone formation in osteoarthritis; In: cells, (published date: 05/11/2022), cells
- Leibniz Institute for Labor Research at TU Dortmund: On the Role of Dopamine in Rheumatoid Arthritis (Accessed: 08.06.2022), Leibniz Institute for Labor Research at TU Dortmund
This article contains general advice only and should not be used for self-diagnosis or treatment. It cannot replace a visit to the doctor.